Tirapazamine pubchem

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August undefined, 2024

Web1 nov 2015 · The ability of tirapazamine (1, 3-amino-1,2,4-benzotriazine 1, 4-dioxide, SR4233) to fix DNA radical lesions is demonstrated by studying the reaction between the antitumor drug and an ... WebNCT00174837: Phase 3 Interventional Completed Head and Neck Squamous Cell Carcinoma

Tirapazamine 27314-97-2 TCI AMERICA

WebTirapazamine C7H6N4O2 CID 135413511 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and … WebTirapazamine Write a review ≥98% (HPLC) Synonym (s): 4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine, SR 259075, SR 4233, Tirazone, Win 59075 Empirical Formula (Hill Notation): C7H6N4O2 CAS Number: 27314-97-2 Molecular Weight: 178.15 Número MDL: MFCD00132954 ID de la sustancia en PubChem: 329825548 NACRES: NA.77 bottineau county food pantry

Tirapazamine = 98 HPLC 27314-97-2

WebProduct Name: Tirapazamine CAS Number: 27314-97-2 IUPAC: 4-hydroxy-1-oxido-1, 2, 4-benzotriazin-1-ium-3-imine PubChem: 33776 Formula: C7H6N4O2 Molecular Mass: … WebTopoisomerase I inhibitors are a class of anticancer drugs with a broad spectrum of clinical activity. However, they have limited efficacy in hepatocellular cancer. Here, we present in … Web9 mar 2014 · Tirapazamine (3-amino-1,2,4-benzotriazine 1,4 dioxide, SR4233) is a bioreductive drug belonging to the aromatic N-oxide family that has a selective toxicity for hypoxic cells ( 19 ). In cell suspensions, tirapazamine is 50- to 500-fold more toxic to hypoxic cells compared with cells in normoxia. bottineau county plat map

Tirapazamine pubchem

WebChemIDplus is moving to PubChem in December 2024. Please see the NLM Technical Bulletin article for more information. Skip Navigation. National Library of Medicine. Help; … WebUnder hypoxic conditions, tirapazamine is a potent cytotoxic agent that induces apoptosis by inducing breaks in single and double stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents like cisplatin. Safety Information Piktogramme GHS07 Signalwort Warning H-Sätze

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WebScienceDirect.com Science, health and medical journals, full text ... Web3 gen 2024 · Tirapazamine (SR259075; Win59075; SR4233)；替拉扎明分子式：C7H6N4O2 分子量：178.15 简介：替拉扎明 Tirapazamine (SR259075; Win59075; SR4233)可在低氧水平下被活化为毒性自由基，是一种实验性抗癌化合物。

WebTirapazamine is an experimental anticancer drug that is activated to a toxic radical only at very low levels of oxygen . Such levels are common in human solid tumors, a phenomenon known as tumor hypoxia. Thus, tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by … Web19 ott 2007 · Tirapazamine, also known as SR-4233, is an experimental anticancer drug that is activated in hypoxic conditions. This activation is very useful as this hypoxic …

WebTirapazamine (4-Hydroxy-1-oxido-1,2,4-benzotriazin-1-ium-3-imine ); >= 98% HPLC; Tirapazamine has been used to evaluate its cytotoxic effect on U-251 MG (glioblastoma …

WebTirapazamine 27314-97-2 東京化成工業株式会社 CAS RN: 27314-97-2 製品コード: T3823 Tirapazamine 純度（試験方法）: >98.0% (HPLC) 別名: チラパザミン 3-アミノベンゾ [ e ] [1,2,4]トリアジン 1,4-ジオキシド SR 259075 3-Aminobenzo [ e ] [1,2,4]triazine 1,4-Dioxide ドキュメント： SDS 規格表試験成績書・各種証明書検索分析チャート大 …

WebBiochem/physiol Actions Under hypoxic conditions, tirapazamine is a potent cytotoxic agent that induces apoptosis by inducing breaks in single and double stranded DNA, as well as … bottineau county gis property mapWebPubChem 识别号. 33776. 存放 ... Chemical Structure - Tirapazamine, cytotoxic agent (ab141976) 2D chemical structure image of ab141976, Tirapazamine, cytotoxic agent. haylard park gentrificationWebBiochem/physiol Actions. Under hypoxic conditions, tirapazamine is a potent cytotoxic agent that induces apoptosis by inducing breaks in single and double stranded … haylan hutches