WebHypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family* ... P. Ratcliffe, D. Mole, Ya-Min Tian, 2006, The Biochemical journal. A photoreactive small-molecule probe for 2 ... Web3 de set. de 2013 · HIF-1 is a heterodimer, consisting of an O 2-regulated HIF-1α subunit and a constitutively expressed HIF-1β subunit (1, 2), ... Mole DR, et al. Genome-wide association of hypoxia-inducible factor (HIF)-1α and HIF-2α DNA binding with expression profiling of hypoxia-inducible transcripts.
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Web9 de dez. de 2005 · The heterodimeric transcription factor HIF (hypoxia-inducible factor), consisting of a labile alpha-subunit and a stable beta-subunit, is a master regulator of … Web9 de out. de 2007 · Abstract. Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix-PAS domain transcription factor that is expressed in all metazoan organisms and is composed of HIF-1α and HIF-1β subunits. Under hypoxic conditions, HIF-1 regulates the transcription of hundreds of genes in a cell type–specific manner. The HIF-1α subunit is … fluxomics software
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Web29 de jun. de 2004 · Blind subterranean mole rats (Spalax, Spalacidae) evolved adaptive strategies to cope with hypoxia that climaxes during winter floods in their burrows. By … Web3 de ago. de 2024 · HIF-1α is the main regulator of hypoxia signaling and is widely expressed (20-22). HIF-1α is involved in the occurrence and development of various liver diseases, including alcoholic liver disease (ALD), nonalcoholic fatty liver disease (NAFLD), viral hepatitis, liver fibrosis, drug-induced liver injury and hepatocellular carcinoma (HCC) … Web20 de jun. de 2024 · HIF protein activity is often beneficial in acute conditions such as myocardial ischemia, sending signals to protect cells and increasing tissue tolerance to hypoxia. ... Mole, D. R. et al. Genome ... greenhill fountains apartments