WebResults Tumorous BHLHE22 mediates the high expression of CSF2, resulting in the infiltration of immunosuppressive neutrophils and monocytes and a prolonged immunocompromised T-cell status. Mechanistically, BHLHE22 binds to the CSF2 promoter and recruits PRMT5, forming a transcriptional complex. PRMT5 epigenetically activates … WebThe Member of Colony-Stimulating Factors CSF1, CSF2, CSF3 and multi-CSF were originally defined by their respective abilities to generate different types of myeloid populations from precursor bone marrow cells in vitro …
CSF2 colony stimulating factor 2 [ Homo sapiens (human) ]
WebCSF2: A gene on chromosome 5q23-q31 that encodes colony stimulating factor 2 (granulocyte-macrophage), a cytokine that controls the production, differentiation and … WebJun 4, 2024 · Granulocyte-macrophage colony-stimulating factor (GM-CSF, or CSF2) was first described in the conditioned media of mouse lung tissue following LPS injection, ... There are four main signaling pathways triggered by CSF2R . After binding of GM-CSF to its receptor, Janus-kinase-2 (JAK-2) is recruited to the cytoplasmic domain of the β … hill field elementary home
Bioinformatics Analysis to Identify Intersection Genes, Associate ...
WebMar 13, 2024 · Fusarium-derived mycotoxin deoxynivalenol (DON) usually induces diarrhea, vomiting and gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small intestinal epithelium using the intestinal porcine epithelial cell line IPEC-J2. We screened out differentially expressed genes (DEGs) using RNA-seq and identified 320 … WebFeb 1, 2024 · The role of the CSF2/CENPE pathway in kidney cells treated with PM and lactoferrin was crucial. In a mouse model, lactoferrin ameliorated PM-indused kidney … WebEnzyme and pathway databases. Reactome. R-CFA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling; R-CFA-5673001 RAF/MAP kinase cascade; R-CFA-912526 Interleukin receptor SHC signaling; ... CSF2. Organism names. Organism. Canis lupus familiaris (Dog) (Canis familiaris) Taxonomic identifier. 9615 NCBI. smart baggy shorts