WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … WebApr 11, 2024 · The combination of doxorubicin and cisplatin has been demonstrated to be effective and well tolerated in cancer patients [ 15 ]. In vitro anti-tumor studies investigating synergistic cisplatin + doxorubicin combination treatment have been carried out with the aim of overcoming multi-drug resistance [ 38 ].
Synergistic Combination Chemotherapy of Lung Cancer: Cisplatin …
WebJul 29, 2013 · Purpose Chemotherapy treatment in premenopausal women has been linked to ovarian follicle loss and premature ovarian failure; the exact mechanism by which this occurs is uncertain. Here, two commonly used chemotherapeutic agents (cisplatin and doxorubicin) were added to a mouse ovary culture system, to compare the sequence of … WebConclusion: TGF-β induced TMEPAI contributes to the reduced response of TNBC treatment to doxorubicin and paclitaxel, but minimal on cisplatin and bicalutamide. Further study is needed to confirm our findings in other growth factor-induced cells, as well as in in vivo model. Keywords: TMEPAI, TGF-β, doxorubicin, paclitaxel. chip mixes
IJMS Free Full-Text Multifaceted Mechanisms of Cisplatin …
WebTitle: Read Free Student Workbook For Miladys Standard Professional Barbering Free Download Pdf - www-prod-nyc1.mc.edu Author: Prentice Hall Subject WebOverall, results show that cisplatin, doxorubicin and cyclophosphamide all specifically induce loss of germ cells, including of spermatogonial stem cells, in the prepubertal mouse testis at concentrations relevant to human therapeutic exposures. U2 - 10.1038/s41598-018-19761-9. DO - 10.1038/s41598-018-19761-9. M3 - Article. VL - 8 WebApr 14, 2024 · The therapeutic efficacy of doxorubicin can be improved by inhibiting Med19 (Mediator Complex Subunit 19), ... DICER promotes autophagy by inhibiting the activation of the PI3K/AKT/mTOR pathway and thus leads to cisplatin resistance non-small cell lung cancer . It is, however, unclear how DICER impacts autophagy in breast cancer paclitaxel ... grants for music therapy programs